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Three grades of grinding beads are produced by OPS Diagnostics, and include Acid Washed, Low Binding, and Molecular Biology Grade. Acid Washed grinding beads are washed with acid to remove small particles and contaminants from the media then oven dried and baked prior to bottling (see Acid Washed ).

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As an alternative to the phenol-chloroform extraction procedure, the salting-out method has the advantage of not using toxic chemicals. It is based on the principle that proteins and other cellular contaminants will precipitate in a saturated salt solution due to their relative hydrophobicity, while DNA does not ( Miller et al., 1988 ).

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